Each turn in On Tour, two ten-sided dice are rolled to make two two-digit numbers. For example, a roll of 3 and 7 creates the numbers 37 and 73. All players write each of those numbers in a state on their map. The regions they can write in are restricted by three cards turned up in the middle of the table.

At the end of the game, each player draws a route on their map, starting with a low number and visiting adjacent states with higher and higher numbers. Players get a point for every state they visit.